-0.52%
6.25%
-9.85%
-27.00%
-33.57%
-34.40%
-19.50%

Company Description

CRISPR Therapeutics AG, a gene editing company, focuses on developing gene-based medicines for serious diseases using its proprietary Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform.Its CRISPR/Cas9 is a gene editing technology that allows for precise directed changes to genomic DNA.The company has a portfolio of therapeutic programs across a range of disease areas, including hemoglobinopathies, oncology, regenerative medicine, and rare diseases.


The company's lead product candidate is CTX001, an ex vivo CRISPR gene-edited therapy for treating patients suffering from transfusion-dependent beta-thalassemia or severe sickle cell disease in which a patient's hematopoietic stem cells are engineered to produce high levels of fetal hemoglobin in red blood cells.It also develops CTX110, a donor-derived gene-edited allogeneic CAR-T investigational therapy targeting cluster of differentiation 19 positive malignancies; CTX120, a donor-derived gene-edited allogeneic CAR-T investigational therapy targeting B-cell maturation antigen for the treatment of relapsed or refractory multiple myeloma; and CTX130, a donor-derived gene-edited allogeneic CAR-T investigational therapy targeting Cluster of Differentiation 70 to treat various solid tumors and hematologic malignancies.In addition, the company develops VCTX210, a gene-edited immune-evasive stem cell-derived product candidate for the treatment of treatment of type 1 diabetes; and pursues various in vivo gene-editing programs that target the liver, lung, muscle, and central nervous system diseases.


It has strategic partnerships with Bayer Healthcare LLC, Vertex Pharmaceuticals Incorporated, ViaCyte, Inc., Nkarta, Inc., and Capsida Biotherapeutics.CRISPR Therapeutics AG was incorporated in 2013 and is headquartered in Zug, Switzerland.

Market Data

Last Price 41.82
Change Percentage -0.52%
Open 42.05
Previous Close 42.04
Market Cap ( Millions) 3569
Volume 1674535
Year High 91.1
Year Low 36.52
M A 50 44.42
M A 200 50.38

Financial Ratios

FCF Yield -5.36%
Dividend Yield 0.00%
ROE -12.15%
Debt / Equity 11.73%
Net Debt / EBIDTA -0.60%
Price To Book 1.84
Price Earnings Ratio -14.88
Price To FCF -18.67
Price To sales 17.7
EV / EBITDA -11.41

News

Business Breakdown

Expected Mid-Term Growth

Segment nΒ°1 -> Collaboration

Expected Growth : 15.0 %

What the company do ?

CRISPR Therapeutics AG collaborates with Vertex Pharmaceuticals to develop gene-editing therapies for beta-thalassemia and sickle cell disease.

Why we expect these perspectives ?

CRISPR Therapeutics AG's 15.0% growth is driven by increasing adoption of gene editing technologies, strategic collaborations, and a strong pipeline of novel therapies. The company's pioneering CRISPR-Cas9 platform has attracted partnerships with leading biopharmaceutical companies, expanding its reach and accelerating innovation. Additionally, growing investments in research and development, and a favorable regulatory environment, contribute to the company's rapid growth.

Segment nΒ°2 -> Grant

Expected Growth : 14.43 %

What the company do ?

CRISPR Therapeutics AG received a grant to support the development of CRISPR-Cas9 gene editing technology for treating genetic diseases.

Why we expect these perspectives ?

The 14.43% growth driven by CRISPR Therapeutics AG's grant is attributed to increasing adoption of gene editing technologies, strategic partnerships, and investments in research and development. Additionally, growing demand for novel therapeutic approaches and expanding applications in oncology, rare genetic diseases, and regenerative medicine contribute to the company's rapid growth.

Crispr Therapeutics Ag Products

Product Range What is it ?
CRISPR-Cas9 Gene Editing A precise genome editing tool that enables precise double-strand breaks in DNA, allowing for efficient and specific editing of genes
CRISPR-Cpf1 Gene Editing A novel genome editing tool that offers improved efficiency and flexibility compared to CRISPR-Cas9, with potential applications in gene therapy and regenerative medicine
Allogenic CAR-T Cell Therapy A type of immunotherapy that uses genetically modified T cells to target and kill cancer cells, with potential applications in treating various types of cancer
Autologous CAR-T Cell Therapy A personalized immunotherapy approach that uses a patient's own T cells to target and kill cancer cells, with potential applications in treating various types of cancer
Gene-Edited Stem Cell Therapies A novel approach that combines gene editing with stem cell therapy to treat genetic diseases and disorders

CRISPR Therapeutics AG's Porter Forces

CRISPR Therapeutics AG has a low threat of substitutes due to its unique gene-editing technology, which is difficult to replicate.

CRISPR Therapeutics AG has a medium bargaining power of customers, as it has a strong pipeline of products, but customers may have some bargaining power due to the competitive landscape.

CRISPR Therapeutics AG has a low bargaining power of suppliers, as it has a strong supply chain and is not heavily reliant on a single supplier.

CRISPR Therapeutics AG has a high threat of new entrants, as the gene-editing space is highly competitive and new companies are entering the market.

CRISPR Therapeutics AG operates in a highly competitive industry, with many established players and new entrants, leading to a high intensity of rivalry.

Capital Structure

Value
Debt Weight 11.25%
Debt Cost 3.95%
Equity Weight 88.75%
Equity Cost 12.91%
WACC 11.90%
Leverage 12.67%

Historical Valuation

Price/Earnings Ratio

Margin Valuation

Peers Valuation

Competitors

Company Rational
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GMAB.CO Genmab A/S develops antibody therapeutics for the treatment of cancer and other diseases primarily in Denmark. The company markets DARZALEX, a human monoclonal antibody for the treatment of patients with …
MRUS Merus N.V., a clinical-stage immuno-oncology company, engages in the discovery and development of bispecific antibody therapeutics in the Netherlands. Its bispecific antibody candidate pipeline includes Zenocutuzumab (MCLA-128), which is in …

Peers Metrics

DCF BETA

Parameters

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WACC
Target Price
41.82$
Current Price
41.82$
Potential
-0.00%

Expected Cash-Flows

Scoring Insights

Peers Group Analysis

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