Celldex Therapeutics, Inc. (CLDX) | Investment Case

1. Company Snapshot

1.a. Company Description

Celldex Therapeutics, Inc., a biopharmaceutical company, engages in developing therapeutic monoclonal and bispecific antibodies for the treatment of various diseases.Its drug candidates include antibody-based therapeutics to treat patients with inflammatory diseases and various forms of cancer.The company's clinical development programs CDX-0159, a Phase I monoclonal antibody that binds the receptor tyrosine kinase KIT and inhibits its activity; CDX-1140, a human agonist monoclonal antibody targeted to CD40, a key activator of immune response, which is found on dendritic cells, macrophages, and B cells, as well as is expressed on various cancer cells; and CDX-527, a bispecific antibody, which uses the company's proprietary active anti-PD-L1 and CD27 human antibodies to couple CD27 costimulation with blockade of the PD-L1/PD-1 pathway to help prime and activate anti-tumor T cell responses through CD27 costimulation.

The company has research collaboration and license agreements with University of Southampton to develop human antibodies towards CD27; Amgen Inc.with exclusive rights to CDX-301 and CD40 ligand; and Yale University.Celldex Therapeutics, Inc.

was incorporated in 1983 and is headquartered in Hampton, New Jersey.

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1.b. Last Insights on CLDX

Celldex Therapeutics' recent momentum is driven by its successful public offering of common stock, which raised approximately $345 million. The company's institutional investor base has also expanded, with SG Americas Securities LLC increasing its stake by 143.2%. Additionally, Celldex has presented positive data from its Phase 2 studies for barzolvolimab, demonstrating rapid and durable improvements in patient quality of life, according to its presentation at the AAD 2026 conference.

1.c. Company Highlights

Last Price	33.87
Change Percentage	1.62%
Open	33.54
Previous Close	33.33
Market Cap ( Millions)	2255
Volume	949360
Year High	34.52
Year Low	17.59
M A 50	28.79
M A 200	25.87

FCF Yield	-9.46%
Dividend Yield	0.00%
ROE	-41.68%
Debt / Equity	0.44%
Net Debt / EBIDTA	9.54%
Price To Book	4.27
Price Earnings Ratio	-8.7
Price To FCF	-10.57
Price To sales	1503.07
EV / EBITDA	-8.01

2. Transcript Summary

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3. NewsRoom

Celldex Therapeutics Spotlights Barzolvolimab as Phase III CSU Data Looms After Fast Enrollment

Apr -15

Source: defenseworld.net

Celldex to Present at Upcoming Investor Conference

Apr -13

Source: globenewswire.com

SG Americas Securities LLC Has $1.29 Million Holdings in Celldex Therapeutics, Inc. $CLDX

Apr -08

Source: defenseworld.net

Celldex Therapeutics Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares

Apr -06

Source: globenewswire.com

Celldex Announces Pricing of $300 Million Public Offering of Common Stock

Apr -02

Source: globenewswire.com

Celldex Announces Proposed Public Offering of Common Stock

Apr -01

Source: globenewswire.com

Celldex Presents Positive Data from Phase 2 Chronic Spontaneous Urticaria and Phase 2 Cold Urticaria and Symptomatic Dermographism Studies Demonstrating Rapid, Profound and Durable Improvements in Patient Quality of Life at AAD 2026

Mar -27

Source: globenewswire.com

Celldex Therapeutics, Inc. (NASDAQ:CLDX) Given Consensus Recommendation of “Moderate Buy” by Brokerages

Mar -23

Source: defenseworld.net

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (11.30%)

6. Segments

Novel Therapeutics

Expected Growth: 11.3%

Celldex Therapeutics' Novel Therapeutics segment growth of 11.3% is driven by increasing adoption of CDX-0158, a promising treatment for chronic refractory gout, and CDX-1140, a novel immunotherapy for various cancers. Strong clinical trial results, strategic partnerships, and expanding pipeline contribute to the segment's growth momentum.

7. Detailed Products

Glembatumumab vedotin

An antibody-drug conjugate designed to treat various types of cancer, including melanoma and breast cancer.

Varlilumab

A monoclonal antibody designed to treat various types of cancer, including melanoma, lung cancer, and kidney cancer.

CDX-0159

A monoclonal antibody designed to treat various types of cancer, including melanoma and breast cancer.

CDX-1140

A monoclonal antibody designed to treat various types of cancer, including breast cancer and lung cancer.

CDX-527

A monoclonal antibody designed to treat various types of cancer, including melanoma and breast cancer.

8. Celldex Therapeutics, Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

Celldex Therapeutics, Inc. has a moderate threat of substitutes due to the presence of alternative treatments and therapies for cancer and immunological disorders.

Bargaining Power Of Customers

Celldex Therapeutics, Inc. has a low bargaining power of customers due to the specialized nature of its products and the lack of alternative options for patients.

Bargaining Power Of Suppliers

Celldex Therapeutics, Inc. has a moderate bargaining power of suppliers due to the presence of multiple suppliers for raw materials and equipment.

Threat Of New Entrants

Celldex Therapeutics, Inc. has a high threat of new entrants due to the growing demand for cancer and immunological disorder treatments and the presence of emerging biotech companies.

Intensity Of Rivalry

Celldex Therapeutics, Inc. operates in a highly competitive industry with many established players, leading to a high intensity of rivalry.

9. SWOT Analysis

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

	Value
Debt Weight	0.59%
Debt Cost	3.95%
Equity Weight	99.41%
Equity Cost	11.94%
WACC	11.89%
Leverage	0.59%

11. Quality Control: Celldex Therapeutics, Inc. passed 3 out of 9 key points

Strong Liquidity

Low Debt

Strong Interest Coverage

Healthy Cash Flow

Operating Efficiency

Strong Return On Equity

Consistent Revenue Growth

Consistent Operating Cash Flow Growth

Margin Improvement

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

PTC Therapeutics

A-Score: 5.8/10

Value: 7.8

Growth: 5.6

Quality: 8.4

Yield: 0.0

Momentum: 9.5

Volatility: 3.3

1-Year Total Return ->

Rhythm Pharma

A-Score: 4.6/10

Value: 6.0

Growth: 5.1

Quality: 4.1

Yield: 0.0

Momentum: 9.5

Volatility: 2.7

1-Year Total Return ->

Ionis Pharmaceuticals

A-Score: 4.2/10

Value: 6.0

Growth: 1.1

Quality: 4.4

Yield: 0.0

Momentum: 10.0

Volatility: 4.0

1-Year Total Return ->

Celldex Therapeutics

A-Score: 3.8/10

Value: 6.7

Growth: 3.0

Quality: 5.1

Yield: 0.0

Momentum: 5.0

Volatility: 3.0

1-Year Total Return ->

Amicus Therapeutics

A-Score: 3.6/10

Value: 0.4

Growth: 7.4

Quality: 4.6

Yield: 0.0

Momentum: 5.5

Volatility: 3.7

1-Year Total Return ->

Denali Therapeutics

A-Score: 3.3/10

Value: 6.7

Growth: 3.7

Quality: 4.5

Yield: 0.0

Momentum: 2.5

Volatility: 2.3

1-Year Total Return ->

Peers Metrics

12.e Scoring ^Insights

12.f DCF ^BETA

Parameters

Short Term Growth

30.07%

Short term Time

10.0

Long-Term Growth

2.00%

WACC

11.89%

Celldex Therapeutics, Inc. - US15117B2025

1. Company Snapshot

1.a. Company Description

1.b. Last Insights on CLDX

1.c. Company Highlights

Fairly Valued

Stable Momentum

Medium Volatility

Earnings Beats

Revenues Miss

Average Growth

Average Quality

Average Yield

Revenues Beats

Weak Momentum

Earnings Miss

2. Transcript Summary

3. NewsRoom

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (11.30%)

6. Segments

Novel Therapeutics

Expected Growth: 11.3%

7. Detailed Products

Glembatumumab vedotin

Varlilumab

CDX-0159

CDX-1140

CDX-527

8. Celldex Therapeutics, Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

Bargaining Power Of Customers

Bargaining Power Of Suppliers

Threat Of New Entrants

Intensity Of Rivalry

9. SWOT Analysis

Strength

Weaknesses

Opportunities

Threats

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

11. Quality Control: Celldex Therapeutics, Inc. passed 3 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

33.87$

Current Price

33.87$

Potential

-0.00%

Expected Cash-Flows

12.e Scoring ^Insights

12.f DCF ^BETA