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1. Company Snapshot

1.a. Company Description

Foghorn Therapeutics Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines targeting genetically determined dependencies within the chromatin regulatory system.The company uses its proprietary Gene Traffic Control platform to identify, validate, and potentially drug targets within the system.It is developing FHD-286, a small molecule inhibitor of the enzymatic activity of BRG1 and BRM for the treatment of metastatic uveal melanoma and relapsed and/or refractory acute myeloid leukemia and myelodysplastic syndrome; and FHD-609, a small molecule protein degrader for BRD9 to treat patients with synovial sarcoma.


The company is also developing an enzymatic inhibitor and a protein degrader as selective modulators of BRM; and ARID1B selective modulators for the treatment of ovarian, endometrial, colorectal, bladder, and gastric cancers.It has a research collaboration and license agreement with Merck Sharp & Dohme Corp.to discover and develop novel oncology therapeutics against a transcription factor target; and with Loxo Oncology to create novel oncology medicines.


Foghorn Therapeutics Inc.was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

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1.b. Last Insights on FHTX

Foghorn Therapeutics' recent performance was negatively impacted by a Q4 loss of $0.30 per share, exceeding the Zacks Consensus Estimate of a loss of $0.29. The company's revenue also lagged estimates, indicating a slowdown in its growth trajectory. Furthermore, the lack of a clear earnings beat in its upcoming report, as indicated by a February 27 article, suggests that the company's financial performance may continue to be a concern. Additionally, the company's pipeline updates, while promising, have not yet translated into significant revenue growth.

1.c. Company Highlights

2. Transcript Summary

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3. NewsRoom

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Foghorn Therapeutics Inc. (NASDAQ:FHTX) Receives Average Recommendation of “Buy” from Analysts

Dec -01

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Foghorn Therapeutics to Participate in the 8th Annual Evercore Healthcare Conference

Nov -25

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Does Foghorn Therapeutics (FHTX) Have the Potential to Rally 133.27% as Wall Street Analysts Expect?

Nov -19

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Foghorn Therapeutics Inc. (FHTX) Reports Q3 Loss, Beats Revenue Estimates

Nov -05

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Foghorn Therapeutics Provides Third Quarter 2025 Financial and Corporate Update

Nov -05

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Foghorn Therapeutics to Participate in Three Upcoming Investor Conferences

Nov -03

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Foghorn Therapeutics Inc. (FHTX) Discusses Pipeline Updates for Selective ARID1B, CBP and EP300 Degrader Programs Transcript

Oct -31

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Foghorn Therapeutics Announces Updates for Selective ARID1B, Selective CBP and Selective EP300 Degrader Programs

Oct -30

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (9.27%)

6. Segments

Medicines

Expected Growth: 9.27%

Foghorn Therapeutics Inc.'s medicines exhibit 9.27% growth driven by increasing demand for precision medicine, advancements in gene regulation, and rising investments in oncology research. Additionally, strategic partnerships, expanded product pipelines, and favorable regulatory environments contribute to this growth.

7. Detailed Products

Gene Regulation Therapies

Foghorn Therapeutics' gene regulation therapies are designed to selectively modulate gene expression to treat a range of diseases, including cancer and genetic disorders.

Chromatin Regulatory Therapies

Foghorn's chromatin regulatory therapies target the chromatin regulatory system to modulate gene expression and treat diseases such as cancer and neurological disorders.

Epigenetic Therapies

Foghorn's epigenetic therapies focus on modifying epigenetic marks to treat diseases such as cancer, neurological disorders, and rare genetic disorders.

Gene Editing Therapies

Foghorn's gene editing therapies utilize CRISPR-Cas9 and other gene editing technologies to treat genetic diseases and disorders.

8. Foghorn Therapeutics Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

Foghorn Therapeutics Inc. has a moderate threat of substitutes due to the presence of alternative treatments and therapies in the market.

Bargaining Power Of Customers

Foghorn Therapeutics Inc. has a low bargaining power of customers due to the lack of concentration of buyers in the market.

Bargaining Power Of Suppliers

Foghorn Therapeutics Inc. has a moderate bargaining power of suppliers due to the presence of multiple suppliers in the market.

Threat Of New Entrants

Foghorn Therapeutics Inc. has a high threat of new entrants due to the attractiveness of the market and the ease of entry.

Intensity Of Rivalry

Foghorn Therapeutics Inc. operates in a highly competitive market with many established players, leading to a high intensity of rivalry.

9. SWOT Analysis

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

Value
Debt Weight -140.34%
Debt Cost 3.95%
Equity Weight 240.34%
Equity Cost 19.71%
WACC 41.83%
Leverage -58.39%

11. Quality Control: Foghorn Therapeutics Inc. passed 4 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

Stock-Card
Ginkgo Bioworks

A-Score: 4.3/10

Value: 7.8

Growth: 3.3

Quality: 4.3

Yield: 0.0

Momentum: 9.5

Volatility: 1.0

1-Year Total Return ->

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Oramed Pharmaceuticals

A-Score: 4.1/10

Value: 7.8

Growth: 4.8

Quality: 3.0

Yield: 0.0

Momentum: 6.0

Volatility: 3.0

1-Year Total Return ->

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Aadi Bioscience

A-Score: 3.9/10

Value: 8.0

Growth: 5.4

Quality: 4.5

Yield: 0.0

Momentum: 3.5

Volatility: 2.0

1-Year Total Return ->

Stock-Card
MeiraGTx

A-Score: 3.8/10

Value: 6.0

Growth: 2.6

Quality: 2.6

Yield: 0.0

Momentum: 9.5

Volatility: 2.3

1-Year Total Return ->

Stock-Card
Foghorn Therapeutics

A-Score: 3.8/10

Value: 8.0

Growth: 5.4

Quality: 6.0

Yield: 0.0

Momentum: 2.0

Volatility: 1.3

1-Year Total Return ->

Stock-Card
Sutro Biopharma

A-Score: 3.0/10

Value: 9.4

Growth: 2.3

Quality: 4.9

Yield: 0.0

Momentum: 0.5

Volatility: 0.7

1-Year Total Return ->

Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

4.36$

Current Price

4.36$

Potential

-0.00%

Expected Cash-Flows