-2.87%
-13.62%
28.48%
-56.25%
-43.77%
-66.61%
-76.45%

Company Description

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing products for improving the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States.Its product candidates are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy; and FTX-6058, an investigational oral fetal hemoglobin inducer for the treatment of sickle cell disease and other hemoglobinopathies, including beta-thalassemia.The company is also discovering drug targets for the treatments of rare neuromuscular, muscular, central nervous system, and hematologic disorders, as well as cardiomyopathies and pulmonary diseases.


Fulcrum Therapeutics, Inc.has research and discovery collaboration agreement with Acceleron Pharma Inc.to identify biological targets to modulate specific pathways associated with a targeted indication within the pulmonary disease space; and has a strategic collaboration and license agreement with MyoKardia, Inc.


to discover, develop, and commercialize novel targeted therapies for the treatment of genetic cardiomyopathies.Fulcrum Therapeutics, Inc.was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

Market Data

Last Price 4.06
Change Percentage -2.87%
Open 4.18
Previous Close 4.18
Market Cap ( Millions) 219
Volume 159193
Year High 13.7
Year Low 2.86
M A 50 4.06
M A 200 5.94

Financial Ratios

FCF Yield -3.99%
Dividend Yield 0.00%
ROE -7.31%
Debt / Equity 3.55%
Net Debt / EBIDTA 267.60%
Price To Book 0.98
Price Earnings Ratio -14.15
Price To FCF -25.06
Price To sales 2.71
EV / EBITDA -6.55

News

Business Breakdown

Expected Mid-Term Growth

Segment nΒ°1 -> Biopharmaceutical

Expected Growth : 10.43 %

What the company do ?

Fulcrum Therapeutics' biopharmaceuticals focus on developing small molecule therapies to modulate gene expression for rare genetic diseases.

Why we expect these perspectives ?

Fulcrum Therapeutics' 10.43% growth in biopharmaceuticals is driven by increasing demand for rare genetic disorder treatments, strategic partnerships, and a strong pipeline of novel therapies. The company's focus on gene regulation and epigenetics is also contributing to its growth, as well as its ability to leverage AI and machine learning in drug discovery.

Fulcrum Therapeutics, Inc. Products

Product Range What is it ?
Fulcrum's FTX-6058 FTX-6058 is a small molecule designed to increase the expression of FUS, a protein that is deficient in individuals with FSHD.
Fulcrum's Losmapimod Losmapimod is a p38Ξ±/Ξ² inhibitor that has been shown to reduce inflammation and improve muscle function in patients with FSHD.
Fulcrum's FTX-020 FTX-020 is a small molecule designed to increase the expression of a key protein involved in the regulation of muscle function.
Fulcrum's Gene Therapy Programs Fulcrum's gene therapy programs are designed to treat genetic disorders by delivering a healthy copy of a gene to cells.

Fulcrum Therapeutics, Inc.'s Porter Forces

Fulcrum Therapeutics, Inc. operates in a niche market with limited substitutes, but the threat of substitutes is still present due to the ongoing research and development in the biotechnology industry.

Fulcrum Therapeutics, Inc. has a diverse customer base, which reduces the bargaining power of individual customers. Additionally, the company's products are specialized, making it difficult for customers to switch to alternative suppliers.

Fulcrum Therapeutics, Inc. relies on a few key suppliers for raw materials and services. While the company has some bargaining power due to its size, the suppliers also have some leverage due to the specialized nature of their products.

The biotechnology industry has high barriers to entry, including significant capital requirements, complex regulatory requirements, and the need for specialized expertise. These barriers make it difficult for new entrants to enter the market.

The biotechnology industry is highly competitive, with many established players and new entrants vying for market share. Fulcrum Therapeutics, Inc. faces intense competition from companies with similar products and technologies.

Capital Structure

Value
Debt Weight 4.40%
Debt Cost 3.95%
Equity Weight 95.60%
Equity Cost 15.68%
WACC 15.16%
Leverage 4.60%

Historical Valuation

Price/Earnings Ratio

Margin Valuation

Peers Valuation

Competitors

Company Rational
LPCN Lipocine Inc., a clinical-stage biopharmaceutical company, focuses on the development of pharmaceutical products for the treatment of neuroendocrine and metabolic disorders. The company's primary development programs are based on oral …
CLSD Clearside Biomedical, Inc., a biopharmaceutical company, focuses on the revolutionizing the delivery of therapies to the back of the eye through the suprachoroidal space. The company offers XIPERE, a triamcinolone …
EYPT EyePoint Pharmaceuticals, Inc., a pharmaceutical company, develops and commercializes ophthalmic products for the treatment of eye diseases in the United States, China, and the United Kingdom. The company provides ILUVIEN, …
RIGL Rigel Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs to treat hematologic disorders, cancer, and rare immune diseases. The company offers Tavalisse, an oral spleen tyrosine kinase …
ASMB Assembly Biosciences, Inc., a clinical-stage biotechnology company, discovers and develops therapeutic candidates for the treatment of hepatitis B virus (HBV) infection in the United States. The company's lead product candidate …

Peers Metrics

DCF BETA

Parameters

Short Term Growth
Short term Time
Long-Term Growth
WACC
Target Price
4.05$
Current Price
4.05$
Potential
-0.00%

Expected Cash-Flows

Scoring Insights

Peers Group Analysis

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