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1. Company Snapshot

1.a. Company Description

Repare Therapeutics Inc., a clinical-stage precision oncology company, discovers and develops therapeutics by using its synthetic lethality approach in Canada and the United States.The company uses its SNIPRx, a proprietary, genome-wide, and CRISPR-enabled platform to systematically discover and develop highly targeted cancer therapies that focuses on genomic instability, including DNA damage repair.Its lead product candidate is RP-3500, an oral small molecule inhibitor for the treatment of solid tumors with specific DNA damage repair-related genomic alterations.


It is also developing RP-6306, which is under Phase I clinical trial for tumors with genetic alterations characterized by CCNE1 amplification; and Polymerase Theta program, a SL target associated with BRCA mutations and other genomic alterations.The company was incorporated in 2016 and is headquartered in Montreal, Canada.

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1.b. Last Insights on RPTX

Repare Therapeutics' recent performance was driven by its Q3 break-even earnings per share, beating the Zacks Consensus Estimate of a loss of $0.35. The company has received a "Hold" rating from brokerages, with an average price target of $3.50. Additionally, Repare Therapeutics entered into a definitive agreement to be acquired by XenoTherapeutics, Inc. for $1.82 per share, plus a contingent value right. The company also announced the acquisition of its Polθ ATPase inhibitor, RP-3467, by Gilead Sciences for up to $30 million.

1.c. Company Highlights

2. Transcript Summary

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3. NewsRoom

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Repare Therapeutics (NASDAQ:RPTX) Trading Up 0.8% – What’s Next?

Feb -20

Source: defenseworld.net

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Repare Shareholders Approve Acquisition by XenoTherapeutics, Inc.

Jan -16

Source: businesswire.com

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Repare Therapeutics (NASDAQ:RPTX) Stock Price Up 0.4% – Here’s Why

Jan -15

Source: defenseworld.net

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Repare Therapeutics Target of Unusually Large Options Trading (NASDAQ:RPTX)

Dec -25

Source: defenseworld.net

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Repare Therapeutics Announces Acquisition of Polθ ATPase Inhibitor, RP-3467, by Gilead Sciences for Up To $30 Million in Total Consideration

Dec -24

Source: businesswire.com

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BRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Repare Therapeutics Inc. (Nasdaq – RPTX), Axalta Coating Systems Ltd. (NYSE – AXTA), Blue Foundry Bancorp (Nasdaq – BLFY), Golden Entertainment, Inc (Nasdaq - GDEN)

Dec -08

Source: globenewswire.com

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$HAREHOLDER ALERT: The M&A Class Action Firm Launches Legal Inquiry for the Merger—RPTX, CNBN, KMB, and KVUE

Dec -04

Source: globenewswire.com

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Halper Sadeh LLC Encourages RPTX, THS, RMBI Shareholders to Contact the Firm to Discuss Their Rights

Nov -27

Source: globenewswire.com

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (10.00%)

6. Segments

Precision Oncology Drugs

Expected Growth: 10.0%

Repare Therapeutics Inc.'s Precision Oncology Drugs segment is driven by increasing demand for targeted therapies, advancements in genetic sequencing, and a growing understanding of cancer biology. The company's proprietary SNIPRx platform enables identification of novel targets, while strategic partnerships and collaborations accelerate drug development, contributing to the 10.0% growth rate.

7. Detailed Products

CAMI

CAMI (Cambridge Membrane Integrity) is a novel, first-in-class, oral small molecule that targets the DNA repair pathway to selectively kill cancer cells.

RP-6306

RP-6306 is a potent and selective inhibitor of the protein kinase ATR, which plays a critical role in the DNA damage response pathway.

RP-7065

RP-7065 is a novel, oral, small molecule inhibitor of the protein kinase CHK1, which is involved in the DNA damage response pathway.

8. Repare Therapeutics Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

The threat of substitutes for Repare Therapeutics Inc. is medium due to the presence of alternative treatments and therapies for cancer and genetic disorders.

Bargaining Power Of Customers

The bargaining power of customers for Repare Therapeutics Inc. is low due to the lack of negotiating power of individual patients and the high demand for innovative cancer treatments.

Bargaining Power Of Suppliers

The bargaining power of suppliers for Repare Therapeutics Inc. is medium due to the presence of multiple suppliers for raw materials and equipment, but the high cost of switching suppliers.

Threat Of New Entrants

The threat of new entrants for Repare Therapeutics Inc. is high due to the growing interest in gene editing and cancer treatment, and the potential for new companies to enter the market.

Intensity Of Rivalry

The intensity of rivalry for Repare Therapeutics Inc. is high due to the presence of established companies and the high competition for market share in the gene editing and cancer treatment market.

9. SWOT Analysis

Strength

Weaknesses

Opportunities

Threats

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

Value
Debt Weight 1.58%
Debt Cost 3.95%
Equity Weight 98.42%
Equity Cost 7.41%
WACC 7.36%
Leverage 1.61%

11. Quality Control: Repare Therapeutics Inc. passed 3 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

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2seventy bio

A-Score: 4.3/10

Value: 7.7

Growth: 4.4

Quality: 4.6

Yield: 0.0

Momentum: 8.5

Volatility: 0.7

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Seer

A-Score: 4.1/10

Value: 8.2

Growth: 4.2

Quality: 4.5

Yield: 0.0

Momentum: 3.5

Volatility: 4.3

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AbCellera Biologics

A-Score: 3.8/10

Value: 7.6

Growth: 1.1

Quality: 4.0

Yield: 0.0

Momentum: 8.0

Volatility: 2.0

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Curis

A-Score: 3.6/10

Value: 9.4

Growth: 3.8

Quality: 5.9

Yield: 0.0

Momentum: 1.5

Volatility: 1.3

1-Year Total Return ->

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Stock-Card
Repare Therapeutics

A-Score: 3.4/10

Value: 7.8

Growth: 4.8

Quality: 3.4

Yield: 0.0

Momentum: 2.0

Volatility: 2.3

1-Year Total Return ->

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Vir Biotechnology

A-Score: 3.3/10

Value: 7.8

Growth: 3.6

Quality: 5.0

Yield: 0.0

Momentum: 2.0

Volatility: 1.3

1-Year Total Return ->

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Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

2.65$

Current Price

2.65$

Potential

-0.00%

Expected Cash-Flows