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1. Company Snapshot

1.a. Company Description

Schrödinger, Inc., together with its subsidiaries, provides physics-based software platform that enables discovery of novel molecules for drug development and materials applications.The company operates in two segments, Software and Drug Discovery.The Software segment is focused on selling its software for drug discovery in the life sciences industry, as well as to customers in materials science industries.


The Drug Discovery segment focuses on building a portfolio of preclinical and clinical programs, internally and through collaborations.The company serves biopharmaceutical and industrial companies, academic institutions, and government laboratories worldwide.Schrödinger, Inc.


was incorporated in 1990 and is based in New York, New York.

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1.b. Last Insights on SDGR

Schrödinger, Inc.'s recent performance was negatively impacted by its Q3 2025 earnings report, which showed a quarterly loss of $0.45 per share, although it topped revenue estimates. The company's software revenue growth of 28% was a positive note, but macroeconomic pressures and a discontinued clinical development program for SGR-2921 may have raised concerns. Additionally, earnings estimate revisions may not support continued stock growth in the near term, according to recent analyst reports.

1.c. Company Highlights

2. Strong Q3 2025 Earnings: Revenue Growth and Improved Operational Efficiency

The company reported a robust third quarter 2025, with total revenue reaching $54 million, a 54% increase from the same period in 2024. Software revenue was $40.9 million, representing 28% year-over-year growth, slightly above expectations. The software gross margin was 73%, indicating a stable and profitable software business. Research and development (R&D) expenses decreased by 16% to $42.8 million, while sales and marketing expenses declined by 8% to $9.5 million, and general and administrative (G&A) expenses dropped by 13% to $21.7 million, primarily due to lower employee-related expenses. The actual EPS loss was $-0.45, better than the estimated loss of $-0.75.

Publication Date: Nov -16

📋 Highlights
  • Revenue Growth:: Total revenue reached $54 million, a 54% YoY increase, with software revenue at $40.9 million (28% YoY growth).
  • Expense Reductions:: Achieved over half of $30 million cost cuts announced in May; $40 million in additional savings from phasing out clinical development, totaling $70 million in savings by 2026.
  • Drug Discovery Guidance:: Raised revenue guidance to $49–52 million (up from $45–50 million) amid strong collaborative portfolio progress.
  • Software Gross Margin:: Maintained 73% margin, with updated 2025 guidance of 73–75% despite pharma industry pressures.

Operational Highlights and Guidance Update

The company is witnessing strong demand for its advanced computational solutions, driven by its differentiated and extensively validated platform. The new computational physics plus AI paradigm is becoming the accepted standard, positioning the company for long-term growth. The company updated its software revenue growth guidance for 2025 to 8%-13% from 10%-15%, reflecting a slowdown in pharma discussions due to industry pressures. However, the company remains confident in its long-term potential, with positive conversations with customers and scheduled renewals on track. As Ramy Farid mentioned, "We are very optimistic about the long-term potential and value of our platform."

Drug Discovery Progress and Expense Reduction

The company has made significant progress in its collaborative portfolio, increasing its drug discovery revenue guidance to $49 million-$52 million. The company has also achieved more than half of its $30 million expense reduction goal, with the remainder to be realized in 2026. This action, combined with the phasing out of independent clinical development activities, is expected to improve the company's long-term profitability profile. The company's highly experienced drug discovery team is pioneering the "predict first" computational approach to drug discovery.

Valuation and Growth Prospects

Analysts estimate next year's revenue growth at 15.8%. The current valuation metrics indicate a Price-to-Sales Ratio of 5.46 and an EV/EBITDA of -6.7. Given the company's improving operational efficiency and growth prospects, the current valuation appears reasonable. However, investors should continue to monitor the company's progress in executing its strategic plans and achieving its guidance.

3. NewsRoom

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Unlocking Hidden Value In Schrodinger's Box

Dec -02

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Miss These Genesis Mission Stocks, and You’ll Regret It for a Decade

Dec -01

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Envestnet Asset Management Inc. Sells 40,529 Shares of Schrodinger, Inc. $SDGR

Nov -16

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Here's Why Schrodinger (SDGR) Is a Great 'Buy the Bottom' Stock Now

Nov -10

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Schrödinger to Present at Jefferies London Healthcare Conference

Nov -06

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Schrödinger, Inc. (SDGR) Q3 2025 Earnings Call Transcript

Nov -06

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Schrodinger, Inc. (SDGR) Reports Q3 Loss, Tops Revenue Estimates

Nov -06

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Schrödinger Reports Third Quarter 2025 Financial Results

Nov -05

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (10.99%)

6. Segments

Software

Expected Growth: 10.43%

Schrödinger's software growth is driven by increasing adoption in pharmaceutical and biotech industries, fueled by the need for computational chemistry and molecular modeling. Growing demand for personalized medicine, gene editing, and drug discovery also contribute to the growth. Additionally, the company's expanding product portfolio and strategic partnerships further accelerate its growth.

Drug Discovery

Expected Growth: 12.53%

Schrödinger's 12.53% growth in Drug Discovery is driven by increasing adoption of its computational platform, FEP+, which accelerates drug development. Growing demand for precision medicine, partnerships with pharma companies, and expansion into new therapeutic areas also contribute to growth. Additionally, the company's AI-driven approach reduces costs and timelines, making it an attractive solution for biotech and pharma companies.

7. Detailed Products

Schrödinger Suites

A comprehensive suite of molecular modeling and computational chemistry software for pharmaceutical, biotech, and academic research

Maestro

A molecular modeling and visualization software for understanding protein-ligand interactions and designing new molecules

LigPrep

A software tool for preparing 3D molecular structures for molecular modeling and simulation

Epik

A software tool for predicting the ionization states of molecules

Phase

A software tool for pharmacophore modeling and 3D QSAR analysis

LiveDesign

A software tool for designing and optimizing small molecules

PyMOL

A molecular visualization software for visualizing and analyzing molecular structures

8. Schrödinger, Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

The threat of substitutes for Schrödinger, Inc. is moderate due to the availability of alternative products in the market.

Bargaining Power Of Customers

The bargaining power of customers is high for Schrödinger, Inc. due to the concentration of buyers in the market.

Bargaining Power Of Suppliers

The bargaining power of suppliers is low for Schrödinger, Inc. due to the availability of multiple suppliers in the market.

Threat Of New Entrants

The threat of new entrants for Schrödinger, Inc. is moderate due to the moderate barriers to entry in the market.

Intensity Of Rivalry

The intensity of rivalry for Schrödinger, Inc. is high due to the high level of competition in the market.

9. SWOT Analysis

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

Value
Debt Weight 18.91%
Debt Cost 3.95%
Equity Weight 81.09%
Equity Cost 11.79%
WACC 10.31%
Leverage 23.31%

11. Quality Control: Schrödinger, Inc. passed 4 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

Stock-Card
Accolade

A-Score: 4.6/10

Value: 8.0

Growth: 5.8

Quality: 3.8

Yield: 0.0

Momentum: 9.5

Volatility: 0.7

1-Year Total Return ->

Stock-Card
Health Catalyst

A-Score: 3.6/10

Value: 9.2

Growth: 5.6

Quality: 4.3

Yield: 0.0

Momentum: 0.5

Volatility: 2.0

1-Year Total Return ->

Stock-Card
Schrödinger

A-Score: 3.4/10

Value: 4.6

Growth: 2.8

Quality: 3.9

Yield: 0.0

Momentum: 7.0

Volatility: 2.3

1-Year Total Return ->

Stock-Card
Teladoc Health

A-Score: 3.4/10

Value: 6.7

Growth: 5.1

Quality: 3.2

Yield: 0.0

Momentum: 3.5

Volatility: 2.0

1-Year Total Return ->

Stock-Card
GeneDx

A-Score: 3.4/10

Value: 0.2

Growth: 4.3

Quality: 5.3

Yield: 0.0

Momentum: 9.5

Volatility: 1.0

1-Year Total Return ->

Stock-Card
Augmedix

A-Score: 3.2/10

Value: 6.4

Growth: 4.6

Quality: 3.5

Yield: 0.0

Momentum: 5.0

Volatility: 0.0

1-Year Total Return ->

Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

17.64$

Current Price

17.64$

Potential

-0.00%

Expected Cash-Flows