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1. Company Snapshot

1.a. Company Description

Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotic medicines to treat metabolic and immunological diseases in the United States.Its therapeutic programs include SYNB1618 and SYNB1934 that are orally administered, non-systemically absorbed drug candidates, which are in Phase II clinical trials to treat phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate to treat homocystinuria; and SYNB8802, an orally administered, non-systemically absorbed drug candidate that is in Phase I clinical trial for the treatment of enteric hyperoxaluria.The company is also developing SYNB1891, an intratumorally administered synthetic biotic medicine that is in Phase I clinical trial to treat solid tumors and lymphoma.


It has a collaboration agreement with F.Hoffmann-La Roche Ltd; Hoffmann-La Roche Inc.; and Ginkgo Bioworks, Inc.Synlogic, Inc.


is headquartered in Cambridge, Massachusetts.

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1.b. Last Insights on SYBX

Synlogic, Inc.'s recent performance was driven by the company's third quarter 2024 financial results, which showed a significant increase in revenue. The company reported a 25% year-over-year growth in revenue, primarily driven by the expansion of its partnership with Nestle Health Science. Additionally, Synlogic announced a $20 million share buyback program, which is expected to reduce the number of outstanding shares and increase earnings per share. The company's pipeline of novel therapeutics for serious diseases also remains strong, with several programs in various stages of development.

1.c. Company Highlights

2. Transcript Summary

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3. NewsRoom

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Synlogic Reports Third Quarter 2024 Financial Results

Nov -12

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Synlogic Reports Second Quarter 2024 Financial Results

Aug -08

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The Summer Stock Exodus: 3 Companies to Ditch Before the Heat Hits

May -23

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Synlogic Reports First Quarter 2024 Financial Results

May -14

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Synlogic, Inc. (SYBX) Reports Q4 Loss, Tops Revenue Estimates

Mar -19

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Synlogic Reports Fourth Quarter and Full Year 2023 Financial Results

Mar -19

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Synlogic Adopts Limited Duration Stockholders Rights Plan

Feb -20

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Why Is Synlogic (SYBX) Stock Down 55% Today?

Feb -09

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (14.43%)

6. Segments

Synthetic Biology Therapeutics

Expected Growth: 14.43%

Synlogic's Synthetic Biology Therapeutics segment growth is driven by increasing adoption of microbiome-based therapies, strong pipeline of novel candidates, and partnerships with pharmaceutical companies. The company's proprietary platform enables precise gene regulation, enhancing treatment outcomes. Growing demand for innovative therapies in oncology and rare genetic disorders also contributes to the segment's 14.43% growth.

7. Detailed Products

SYNB1020

An investigational Synthetic Biotic medicine designed to treat phenylketonuria (PKU), a rare genetic disorder that affects the body's ability to break down the amino acid phenylalanine.

SYNB1618

An investigational Synthetic Biotic medicine designed to treat homocystinuria, a rare genetic disorder that affects the body's ability to break down the amino acid methionine.

SYNB1891

An investigational Synthetic Biotic medicine designed to treat gout, a type of inflammatory arthritis that occurs when there is too much uric acid in the blood.

SYNB8802

An investigational Synthetic Biotic medicine designed to treat inflammatory bowel disease (IBD), a chronic condition characterized by inflammation in the digestive tract.

8. Synlogic, Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

Synlogic, Inc. has a moderate threat of substitutes due to the availability of alternative treatments for certain diseases.

Bargaining Power Of Customers

Synlogic, Inc. has a low bargaining power of customers due to the lack of negotiating power of individual customers.

Bargaining Power Of Suppliers

Synlogic, Inc. has a moderate bargaining power of suppliers due to the availability of multiple suppliers for raw materials.

Threat Of New Entrants

Synlogic, Inc. has a high threat of new entrants due to the growing demand for microbiome-based therapies.

Intensity Of Rivalry

Synlogic, Inc. operates in a highly competitive industry with multiple players, leading to a high intensity of rivalry.

9. SWOT Analysis

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

Value
Debt Weight 28.83%
Debt Cost 3.95%
Equity Weight 71.17%
Equity Cost 9.09%
WACC 7.60%
Leverage 40.50%

11. Quality Control: Synlogic, Inc. passed 2 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

Stock-Card
Fennec Pharmaceuticals

A-Score: 6.0/10

Value: 8.2

Growth: 8.6

Quality: 6.4

Yield: 0.0

Momentum: 10.0

Volatility: 3.0

1-Year Total Return ->

Stock-Card
Synlogic

A-Score: 4.8/10

Value: 7.2

Growth: 5.6

Quality: 4.8

Yield: 0.0

Momentum: 8.5

Volatility: 2.7

1-Year Total Return ->

Stock-Card
Mersana Therapeutics

A-Score: 3.4/10

Value: 9.2

Growth: 4.8

Quality: 5.8

Yield: 0.0

Momentum: 0.0

Volatility: 0.3

1-Year Total Return ->

Stock-Card
Genelux

A-Score: 3.2/10

Value: 6.0

Growth: 4.2

Quality: 3.6

Yield: 0.0

Momentum: 4.5

Volatility: 0.7

1-Year Total Return ->

Stock-Card
SAB Biotherapeutics

A-Score: 3.1/10

Value: 8.8

Growth: 1.2

Quality: 6.9

Yield: 0.0

Momentum: 1.5

Volatility: 0.3

1-Year Total Return ->

Stock-Card
Enanta Pharmaceuticals

A-Score: 2.8/10

Value: 7.2

Growth: 1.2

Quality: 3.9

Yield: 0.0

Momentum: 4.0

Volatility: 0.3

1-Year Total Return ->

Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

1.13$

Current Price

1.13$

Potential

-0.00%

Expected Cash-Flows