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1. Company Snapshot

1.a. Company Description

Travere Therapeutics, Inc., a biopharmaceutical company, focuses on the identification, development, commercialization, and delivering of therapies for the treatment of rare diseases.Its marketed products include Chenodal, a synthetic oral form of chenodeoxycholic acid for the treatment of radiolucent stones in gallbladders; Cholbam, a cholic acid capsule to treat pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects, as well as for adjunctive treatment of patients with peroxisomal disorders; and Thiola and Thiola EC, a tiopronin tablet for the treatment of homozygous cystinuria.The company's product candidates also consist of Sparsentan, which is in Phase III clinical trial for the treatment of focal segmental glomerulosclerosis and immunoglobulin A nephropathy; and TVT-058, a novel investigational human enzyme replacement candidate, which is in Phase I/II clinical trials for the treatment of classical homocystinuria.


It has a cooperative research and development agreement with National Institutes of Health's National Center for Advancing Translational Sciences and patient advocacy organizations, CDG Care, and Alagille Syndrome Alliance for the identification of potential small molecule therapeutics for NGLY1 deficiency and Alagille syndrome.The company was formerly known as Retrophin, Inc.and changed its name to Travere Therapeutics, Inc.


in November 2020.Travere Therapeutics, Inc.was incorporated in 2008 and is headquartered in San Diego, California.

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1.b. Last Insights on TVTX

Travere Therapeutics' recent performance was driven by strong commercial momentum, particularly with FILSPARI in the IgAN market. The company's Q2 2025 earnings report showed a narrower loss per share than expected, with revenue growth fueled by increased FILSPARI sales. Recent presentations at investor conferences, including Cantor Global Healthcare and Wells Fargo Healthcare conferences, highlighted the company's growth prospects. Additionally, the FDA waiving an advisory committee for Filspari's FSGS filing has boosted investor confidence. The company's strategic priorities are on track, positioning it for near- and long-term growth.

1.c. Company Highlights

2. Travere Therapeutics' Q3 2025 Earnings: Strong Revenue Growth and Commercial Execution

Travere Therapeutics reported a robust financial performance in Q3 2025, with total revenue reaching $164.9 million, driven by U.S. net product sales of $113.2 million, with FILSPARI contributing $90.9 million. The company's actual EPS came out at $0.28, significantly beating estimates of -$0.31. This strong financial performance was accompanied by continued significant revenue growth, with analysts estimating next year's revenue growth at 37.4%. The company's cash, cash equivalents, and marketable securities totaled approximately $254.5 million as of September 30, 2025.

Publication Date: Nov -25

📋 Highlights
  • FILSPARI Q3 Net Sales:: $91 million, driven by sustained commercial execution in IgA nephropathy.
  • Total Revenue Growth:: $164.9 million in Q3, including $51.7 million in license/collaboration revenue.
  • Cash Reserves:: $254.5 million in cash, cash equivalents, and marketable securities as of September 30, 2025.
  • KDIGO Guidelines Validation:: External endorsement of FILSPARI’s dual ERA mechanism for IgA nephropathy treatment.
  • Pegtibatinase Scale-Up:: Manufacturing campaigns completed, enabling FDA engagement and HARMONY trial restart in 2026.

Commercial Performance and Growth Drivers

The company's commercial performance was a key highlight, with FILSPARI's growth in IgA nephropathy driven by sustained commercial excellence, consistent real-world outcomes, and robust long-term data reinforcing its differentiated profile. As Peter Heerma, Chief Commercial Officer, noted, "The third quarter marked another period of strong commercial performance and continued momentum for FILSPARI in IgA nephropathy." FILSPARI net product sales reached approximately $91 million in the third quarter, representing another quarter of strong growth.

Valuation and Growth Expectations

With a P/S Ratio of 7.35, the market is pricing in significant revenue growth expectations. Given the company's strong commercial execution and growth drivers, it remains to be seen whether Travere Therapeutics can meet or exceed these expectations. The company's EV/EBITDA ratio stands at -81.64, indicating that the market is pricing in significant future growth. As the company continues to advance its pipeline and prepare for potential approvals and launches, investors will be watching closely to see if the company's growth prospects are realized.

Pipeline Advancements and Future Prospects

The company is making significant progress in its pipeline, with preparations underway for a potential FDA approval in FSGS and advancements in the manufacturing scale-up of pegtibatinase to support restarting enrollment in the pivotal HARMONY study in 2026. The company's agreement with the PMDA of Japan to initiate 2 Phase III trials for sparsentan in FSGS and Alport syndrome is also a positive development. As Eric Dube, President and Chief Executive Officer, noted, "We've entered the final months of 2025 confident in sustaining FILSPARI's growth in IgAN, executing on a potential approval and launch in FSGS, and advancing our pipeline with focus."

3. NewsRoom

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3 Potential Mid-Cap Biotech Buyout Targets In 2026

Dec -03

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Travere Therapeutics (NASDAQ:TVTX) Reaches New 52-Week High – Still a Buy?

Nov -30

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Travere Therapeutics: Thriving Kidney Franchise Set To Soar On January PDUFA

Nov -26

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Why This Fund Trimmed a $161 Million Travere Position After a 100% Rally

Nov -18

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Campbell & CO Investment Adviser LLC Makes New $241,000 Investment in Travere Therapeutics, Inc. $TVTX

Nov -18

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Travere Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Nov -10

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Travere Therapeutics Announces Late-Breaking Data from Phase 3 DUPLEX Study of FILSPARI in FSGS Presented at the American Society of Nephrology (ASN) Kidney Week 2025

Nov -06

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Travere Therapeutics to Participate at Upcoming Investor Conferences

Nov -04

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (9.73%)

6. Segments

Tiopronin Products

Expected Growth: 9.27%

Travere Therapeutics' Tiopronin Products' 9.27% growth is driven by increasing adoption in cystinuria treatment, expanded distribution channels, and growing awareness of the product's benefits in reducing kidney stone recurrence. Additionally, strategic partnerships and investments in R&D have enhanced the product's efficacy and patient outcomes, contributing to its rapid growth.

FILSPARI

Expected Growth: 11.3%

FILSPARI's 11.3% growth is driven by increasing adoption in rare kidney diseases, strong commercial execution, and expanding label indications. Additionally, Travere's strategic partnerships and investments in research and development are expected to fuel further growth.

7. Detailed Products

Filgotinib

An oral, selective JAK1 inhibitor for the treatment of rheumatoid arthritis and other inflammatory diseases

Sparsentan

A dual endothelin receptor antagonist for the treatment of focal segmental glomerulosclerosis (FSGS) and IgA nephropathy

TRC101

A novel, orally available, non-absorbed, polymer-based treatment for chronic kidney disease (CKD) patients with metabolic acidosis

8. Travere Therapeutics, Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

Travere Therapeutics, Inc. has a moderate threat of substitutes due to the presence of alternative treatments and therapies for kidney diseases.

Bargaining Power Of Customers

Patients and healthcare providers have limited bargaining power due to the specialized nature of Travere Therapeutics, Inc.'s products and services.

Bargaining Power Of Suppliers

Travere Therapeutics, Inc. has a moderate bargaining power of suppliers due to the presence of multiple suppliers for raw materials and services.

Threat Of New Entrants

The biotechnology industry is highly competitive, and new entrants can easily disrupt the market with innovative products and services.

Intensity Of Rivalry

The biotechnology industry is highly competitive, and Travere Therapeutics, Inc. faces intense rivalry from established players and new entrants.

9. SWOT Analysis

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

Value
Debt Weight 65.55%
Debt Cost 3.95%
Equity Weight 34.45%
Equity Cost 7.38%
WACC 5.13%
Leverage 190.32%

11. Quality Control: Travere Therapeutics, Inc. passed 2 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

Stock-Card
Sage Therapeutics

A-Score: 4.9/10

Value: 7.4

Growth: 6.1

Quality: 4.8

Yield: 0.0

Momentum: 9.0

Volatility: 2.3

1-Year Total Return ->

Stock-Card
Travere Therapeutics

A-Score: 3.9/10

Value: 6.2

Growth: 2.3

Quality: 3.8

Yield: 0.0

Momentum: 9.0

Volatility: 2.0

1-Year Total Return ->

Stock-Card
Bluebird Bio

A-Score: 3.6/10

Value: 9.8

Growth: 3.6

Quality: 5.1

Yield: 0.0

Momentum: 0.0

Volatility: 3.3

1-Year Total Return ->

Stock-Card
SAB Biotherapeutics

A-Score: 3.1/10

Value: 8.8

Growth: 1.2

Quality: 6.9

Yield: 0.0

Momentum: 1.5

Volatility: 0.3

1-Year Total Return ->

Stock-Card
Veru

A-Score: 2.9/10

Value: 6.6

Growth: 0.9

Quality: 4.0

Yield: 0.0

Momentum: 5.0

Volatility: 0.7

1-Year Total Return ->

Stock-Card
Lyra Therapeutics

A-Score: 2.5/10

Value: 6.4

Growth: 4.7

Quality: 3.4

Yield: 0.0

Momentum: 0.5

Volatility: 0.0

1-Year Total Return ->

Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

35.0$

Current Price

35$

Potential

-0.00%

Expected Cash-Flows