-0.71%
8.87%
-7.90%
-11.56%
1.16%
80.37%
93.09%

Company Description

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis.The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation.Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial.


The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally.It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc.Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

Market Data

Last Price 438.4
Change Percentage -0.71%
Open 443.56
Previous Close 441.52
Market Cap ( Millions) 112901
Volume 1047967
Year High 519.88
Year Low 377.85
M A 50 438.71
M A 200 458.47

Financial Ratios

FCF Yield -1.03%
Dividend Yield 0.00%
ROE -2.88%
Debt / Equity 10.89%
Net Debt / EBIDTA -683.08%
Price To Book 7.24
Price Earnings Ratio -235.74
Price To FCF -97.01
Price To sales 10.64
EV / EBITDA 211.25

News

Business Breakdown

Expected Mid-Term Growth

Segment nΒ°1 -> Pharmaceutical

Expected Growth : 8.0 %

What the company do ?

Vertex Pharmaceuticals Incorporated is a biotechnology company that develops and commercializes medicines for serious diseases, including cystic fibrosis, sickle cell disease, and alpha-1 antitrypsin deficiency.

Why we expect these perspectives ?

Vertex Pharmaceuticals' 8.0% growth is driven by strong sales of cystic fibrosis treatments, including Trikafta and Symdeko, as well as increasing adoption of its pipeline products, such as VX-147 for APOL1-mediated kidney disease. Additionally, the company's expanding presence in international markets and strategic collaborations contribute to its growth momentum.

Vertex Pharmaceuticals Incorporated Products

Product Range What is it ?
TRIKAFTA A prescription medicine used for the treatment of cystic fibrosis in patients aged 12 years and older who have at least one F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
SYMDEKO A prescription medicine used for the treatment of cystic fibrosis in patients aged 12 years and older who have two copies of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
ORKAMBI A prescription medicine used for the treatment of cystic fibrosis in patients aged 2 years and older who have two copies of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
KALYDECO A prescription medicine used for the treatment of cystic fibrosis in patients aged 4 months and older who have one of the following mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N, or S549R.
INCIVEK A prescription medicine used for the treatment of genotype 1 chronic hepatitis C virus (HCV) infection in adults with compensated liver disease, including cirrhosis.

Vertex Pharmaceuticals Incorporated's Porter Forces

Vertex Pharmaceuticals Incorporated has a moderate threat of substitutes due to the presence of alternative treatments for cystic fibrosis and other diseases. However, the company's strong pipeline and innovative products reduce the threat of substitutes.

Vertex Pharmaceuticals Incorporated has a low bargaining power of customers due to the lack of negotiating power of individual patients and the high demand for its products.

Vertex Pharmaceuticals Incorporated has a low bargaining power of suppliers due to the company's strong relationships with its suppliers and the lack of dependence on a single supplier.

Vertex Pharmaceuticals Incorporated has a low threat of new entrants due to the high barriers to entry in the pharmaceutical industry, including the need for significant research and development investments and regulatory approvals.

Vertex Pharmaceuticals Incorporated operates in a highly competitive industry with several established players, leading to a high intensity of rivalry. The company must continuously innovate and invest in research and development to maintain its market position.

Capital Structure

Value
Debt Weight 4.40%
Debt Cost 5.87%
Equity Weight 95.60%
Equity Cost 5.87%
WACC 5.87%
Leverage 4.60%

Historical Valuation

Price/Earnings Ratio

Margin Valuation

Peers Valuation

Competitors

Company Rational
INVA Innoviva, Inc. engages in the development and commercialization of pharmaceuticals in the United States and internationally. Its products include RELVAR/BREO ELLIPTA, a once-daily combination medicine consisting of a LABA, vilanterol …
REGN Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various diseases worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular …
ABBV AbbVie Inc. discovers, develops, manufactures, and sells pharmaceuticals in the worldwide. The company offers HUMIRA, a therapy administered as an injection for autoimmune and intestinal BehΓ§et's diseases; SKYRIZI to treat …
MCK McKesson Corporation provides healthcare services in the United States and internationally. It operates through four segments: U.S. Pharmaceutical, International, Medical-Surgical Solutions, and Prescription Technology Solutions (RxTS). The U.S. Pharmaceutical segment …
MRNA Moderna, Inc., a biotechnology company, discovers, develops, and commercializes messenger RNA therapeutics and vaccines for the treatment of infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases, and auto-immune diseases in the …

Peers Metrics

DCF BETA

Parameters

Short Term Growth
Short term Time
Long-Term Growth
WACC
Target Price
438.4$
Current Price
438.4$
Potential
-0.00%

Expected Cash-Flows

Scoring Insights

Peers Group Analysis

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