Company Story
2003 - Marinus Pharmaceuticals, Inc. was founded by Christopher M. Cashman.
2004 - The company acquired the rights to ganaxolone, a novel neurosteroid, from the National Institutes of Health.
2005 - Marinus Pharmaceuticals, Inc. completed a Phase 1 clinical trial of ganaxolone in healthy adults.
2007 - The company initiated a Phase 2 clinical trial of ganaxolone in patients with partial onset seizures.
2010 - Marinus Pharmaceuticals, Inc. completed a Phase 2 clinical trial of ganaxolone in patients with refractory partial onset seizures.
2012 - The company initiated a Phase 3 clinical trial of ganaxolone in patients with refractory partial onset seizures.
2014 - Marinus Pharmaceuticals, Inc. completed an initial public offering (IPO) and listed on the NASDAQ stock exchange.
2016 - The company reported top-line results from its Phase 3 clinical trial of ganaxolone in patients with refractory partial onset seizures.
2019 - Marinus Pharmaceuticals, Inc. received Breakthrough Therapy designation from the FDA for ganaxolone in the treatment of CDKL5 deficiency disorder.
2020 - The company reported positive results from its Phase 2 clinical trial of ganaxolone in patients with CDKL5 deficiency disorder.